Institution:
Pathophysiology Department, Tongji Medical College, Huazhong University of Science and Technology

Education and Training:
1975-1978 General Medicine, Tongji (Wuhan) Medical College, Wuhan, China
1985-1988 Post Graduate Training in Biochemistry, Tongji Medical University, Wuhan, China
1992-1993 Postdoctoral Research in Biochemistry, Siena University, Siena, Italy
1993-1996 Postdoctoral Research in Alzheimer disease, NYS Institute for Basic Research, SI, NY, USA

Honors and Awards:
2004 Changjiang Scholar, National Education Committee of China
2004 First-grade Award of Natural Science Research in Alzheimer disease, National Education Committee
2002 First-grade Award of Natural Science Research in Alzheimer disease, Chinese Medical Association
2000 Second-grade Award of Natural Science Research in Alzheimer disease, Government of Hubei Province
1999 National Outstanding-Young Scientist Fund

Selected publications:
Zhang YJ, Xu YF, Liu YH, Yin J, Li HL, Wang Q and Wang JZ. Peroxynitrite induces Alzheimer-like tau modifications and accumulation in rat brain and its underlying mechanisms. FASEB J. in press
Liu R, Pei JJ, Wang XC, Zhou XW, Tian Q, Winblad B, Wang JZ. Acute anoxia induces tau dephosphorylation through protein phosphatase-2A activation in rat brain slices. J Neurochem. 2005, 94(5):1225-34.
Liu SJ, Zhang JY, Li HJ, Fang ZY, Wang Q, Deng HM, Gong C, Iqbal K, Wang JZ. Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain. J Biol Chem. 2004, 279(48):50078-88.
Liu SJ, Zhang AH, Li HL, Wang Q, Deng HM, Netzer, WJ, Xu H, Wang JZ. Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory. J Neurochem, 2003, 87:1333-44.
Hu YY, He SS, Wang XC, Duan QH, Grundke-Iqbal I, Iqbal K, Wang JZ. Level of nonphosphorylated tau in CSF of Alzhemer disease: An Ultrasensitive bienzyme-substrate-recycle ELISA. Am J Pathol, 2002, 160(4): 1269-78,
Wang JZ, Grundke-Iqbal I, Iqbal K. Glycosylation of microtubule-associated protein tau: an abnormal posttranslational modification in Alzheimer disease. Nat Med. 1996,2(8): 870-6