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About ISP History Structure    


PDF(242KB)PDF version of ISP Consitution 2002




The Preamble of The ISP Constitution (last version accepted at the 4th ISP Congress in Budapest, 2002) states that “Pathophysiology is a modern integrative biomedical science founded on basic and clinical research that is concerned with the mechanisms responsible for the initiation, development, and treatment of pathological processes in humans and animals. The International Society for Pathophysiology (ISP) ….. is a non-governmental, non-profit organization uniting specialists of experimental physiology, clinical medicine and modern biology who work on the problems of human and animal pathophysiology. The ISP cooperates with related international scientific societies and associations.”

Osmo Hanninen, who served as the organizing Secretary General of the Centennial Congress of the IUPS (International Society of Physiological Sciences) held in Helsinki (1989), recalled, that some time before the Congress started he got a message from academician Georgy N. Kryzhanovsky, of Moscow, suggesting they meet. They agreed to do this during the Congress. Vladimir Shinkarenko, who spoke fluent English, was also present. During the discussion Kryzhanovsky suggested that they organize a Constituent Congress of the International Society for Pathophysiology in Moscow. He asked if H?nninen and the Finnish Physiological Society were willing to help. He got the promise and the help in time.

It should be mentioned that Ulrich Zwiener?, Chairman of the Society for Pathological and Clinical Physiology of the German Democratic Republic (GDR), and later a founding member of The ISP, did also much in the field of pathophysiology for the development of international scientific relations.  This included organizing the International Congress for Pathophysiology in the GDR (Leipzig, 1984) when he put forward the idea of establishing an "International Society of Pathophysiology” (see R. Bauer: Acta Physiol. Hung. 92: 93-95, 2005).



Bronze medallion edited as a present to the participants for commemorating the founding congress of ISP in Moscow, 1991 (diameter: 6 cm)

The Organizing and Scientific Program Committee of the Congress consisted of 28 acknowledged experts in physiological sciences from all over the world.

Kryzhanovsky served as President of the Congress, and Shinkarenko as the Secretary General. A few other committees – e.g. Teaching - were also established.

As previously agreed for organizational reasons, two headquarters were formed: the main organizing office was in Moscow. However, matters that concerned participants from countries other than the USSR (i.e. registrations, scientific communications, correspondence) as well as compiling the scientific publications of the Congress were taken care of at the Department of Physiology, University of Kuopio (Finland) headed by H?nninen. The communication between these two offices was first handled by couriers. The employees of one of the sponsors, Orion Pharmaceutica, helped a lot in this context. Even the help of the Finnish Embassy in Moscow was enjoyed. Later on Shinkarenko managed to get smoother telephone, fax and e-mail connections.

The National Organizing Committee – Kryzhanovsky and Shinkarenko as the key executive members – managed in spite of a number of logistic and administrative difficulties to organize a large scale international congress with a fine scientific program and interesting social events (including ballet and opera in the Bolshoi Theatre, The Moscow Circus, city tours, etc).

More than 1000 participants attended the Congress and more than 4000 abstracts were published in the Abstract book.

The draft Constitution of The ISP was elaborated in Finland using the Constitution of the International Council of Laboratory Animal Science as background material with a number of modifications taken mostly from other sources.

In the General Assembly of the newly established ISP in Moscow, Kryzhanovsky was elected to serve as President and Shinkarenko as Secretary General of the Society.

The Constitution was adopted. Some of the participants suggested that The ISP would be a society of societies, but others proposed to allow individual members as well. It was decided that individuals could be ISP members too. The Council was established, which authorized Toshikazu Yoshikawa to negotiate about starting a new journal: Pathophysiology, the official journal of The ISP.  It was also decided to join the IUPS with The ISP as an Associate Member.

During the  meeting Japan won the voting against Finland to host the 2nd ISP Congress.

After the Congress, Kryzhanovsky and Shinkarenko took care of the official registration of the new Society, while Finland provided the supporting documents concerning international matters.



The Second Congress was run under the presidency of Yukata Oomura, with Tosihiie Sakata his “right hand” as Secretary General.

The Congress was held at the modern Kyoto International Conference Hall and run successfully with 1249 participants according to the List of Participants, however, in reality somewhat less than 1000 attended. Unfortunately, the economic situation in certain countries had deteriorated further and far fewer participants than expected from those countries were able to participate.

The congress program included 5 plenary and one special lecture, 3 round table discussions, 37 symposia, 84 workshops, 230 posters, and 6 satellite symposia.

Oomura was elected to serve as ISP President and H?nninen as President Elect, while Shinkarenko continued as the Secretary General. Sakata was elected as Treasurer.

Finland was selected to host the 3rd International Congress of Pathophysiology, ISP-1998.

On behalf of  The ISP, Oomura signed the agreement with Elsevier Publishing House to start the journal Pathophysiology. The Editorial Board was elected in Kyoto.



Osmo H?nninen served as the President of the Congress and Chandan K Sen as its Secretary General.

The hosting organization was the Finnish Physiological Society, its treasurer Esa Hohtola taking care of economic matters. As with the preparation of the constituent congress of The ISP, again Mrs. Anu Laine (Kuopio) was of most valuable help during the planning phase. Mustafa Atalay was responsible for all the publications. About 900 participants from 51 countries attended During ISP-98, approximately 350 invited lectures were delivered, and about 1000 communications were presented.

The Congress was held in Lahti at the Cultural Center.

Congress participants sailed over Lake Vesij?rvi in sunshine and calm waters.

The Abstracts were published as a special issue of Pathophysiology (Vol 5 Supplement 1, 1998) by Elsevier. The Program Book contained the Index of the Abstracts’ volume.

At the Council meeting H?nninen was elected to serve as ISP President and Emil Monos as President Elect because Hungary was chosen to host the 4th International Congress of Pathophysiology, ISP-2002. Lajos Szollár was elected as ISP Secretary General. Sakata continued as ISP Treasurer. The President was authorized to travel to China to study the suggested venue in Beijing and to report to The ISP Executive Committee.



With Emil Monos as President and Lajos Szollár as Secretary General, the ISP-2002 was held at the E?tv?s Lóránd  University Convention Centre located on the banks of the River Danube on the Buda side of the Hungarian Capital. The Hungarian Physiological Society was the hosting society.

The 6th International Conference of the European Society for Noninvasive Cardiovascular Dynamics was integrated with the program of The ISP-2002 in the form of two congress symposia.

Seven hundred abstracts received from 48 countries represented around 2000 scientists. The total number of registered participants was 660. Based on the preliminary registrations in excess of 3000, the attendance could have been significantly higher, had the alarming political and economic events of 2001 – the attack against the World Trade Centre, New York - not deterred quite a few potential attendees and sponsors from participating.

The congress program covered a wide range of scientific topics from mechanisms of human and animal diseases through to therapeutic interventions. In addition, advanced methods of pathophysiological education were addressed.

One of the main objectives of the Local Organizing Committee was to promote and stimulate communication between experts both during and following the Congress. Therefore, in the Abstract volume (Acta Physiologica Hungarica 89/1-3, 2002) and in the Final Program booklet, each paper abstract featured the e-mail address of the speaker. In addition, the Abstract volume contained a full name index. Further, this was the first ISP congress organized by using a website (http//:isp2002.sote.hu).

Congress participants also received a memorial bronze medal with the logo of ISP-2002 on one side, and a portrait of Hungarian King István (Saint Stephen) on the other, to commemorate the millennial historical past of Hungary. Cultural events included the opening ceremony with musical performance by The Jen? Hubay Chamber Orchestra, and an organ concert by Norbert Balogh in Matthias Cathedral. Several site-seeing programs and pre- as well as post-congress tours in Hungary were also offered. A banquet aboard the Danube cruiser “Európa” with a spectacular firework display closed the Congress.

The Ceremonial Hall of the Council of Semmelweis University Budapest hosted the leadership electoral meeting. Rector Péter Sótonyi, in the capacity of host, awarded Ignác Semmelweis medals to the preceding presidents of ISP. In a secret ballot Emil Monos (Hungary) and Qi-de Han (China) were unanimously voted President and President Elect, respectively, for a 4-year term. Osamu Matsuo (Japan) was elected the Treasurer, Amanda Lochner (Republic of South Africa) became Vice President, and Serguei V. Grachev (Russia) Executive Vice President. Vice President David H. Lewis (Sweden), Editor of Pathophysiology Yoshikawa (Japan), and Secretary General Lajos Szollár (Hungary) were confirmed in their posts. After hearing the reports from The ISP officials, election and re-election of the 25 board members took place at the General Assembly of the ISP. Recipients of 10 junior awards were announced. Following bid presentations of a uniformly high standard, the venues of the next ISP Congresses were decided by ballot: Beijing in 2006, and preliminarily, Montreal in 2010 (the latter to be confirmed at the Beijing Congress after receiving the report on preparations).



The fifth International Congress of Pathophysiology (www.isp2006.org.cn) was organized in the China International Conference Centre, Beijing by the Chinese Association of Pathophysiology with the support of the China Association for Science and Technology. Qi-de Han served as President of the Congress and Liling Wu, as the Secretary General.

The Congress Organizers received 1076 abstracts from 42 countries. The total number of registered participants was 928. 390 oral presentations were programmed in 34 congress symposia, 686 abstracts were presented in 12 poster sections. 15 internationally renowned guest speakers delivered their plenary lectures, some after the Opening Ceremony and the remainder, before the Closing Ceremony. Six satellite meetings were held. Ten young scientists poster prizes were awarded. 

The presentations of the Congress covered a wide range of scientific topics from the mechanisms of human and animal diseases to therapeutic interventions. The scale of observations ranged from molecules to organs, or even to the whole organism. Integrative approaches were accentuated in both research and pathophysiological education. 

Abstracts of the presentations were published in the Chinese Journal of Pathophysiology (Vol 22, 13, 2006), the official journal of the Chinese Association of Pathophysiology.  

The Congress was run smoothly, and the spirit of the meeting was imbued with the humanistic flavour of traditional and modern Chinese culture, and with the remarkable progress of Chinese science.

Following tradition, The ISP had its administrative meetings during and immediately after the Congress. The General Assembly elected for the next four year period Qi-de Han (China) to serve as ISP President and Youyi Zhang (China) as ISP Secretary General. Other Officers (2006-2010): Emil Monos (Hungary) Past President, Pavel Hamet (Canada) President Elect, Yuriy Arkhipenko (Russia) Vice President, Stephen Greenwald (England) Vice President, Youyi Zhang (China) Secretary General, László Rosivall (Hungary) Treasurer, Osmo H?nninen  (Finland) Editor-in-Chief of Pathophysiology. Further, 24 Council Members were elected/re-elected by the General Assembly for 2006-2010. Elected honorary life members of The ISP are Georgy N. Kryzhanovsky (Russia) Founding Honorary President, Juraj Korpas (Slovakia) Honorary Council Member, Yukata Oomura (Japan) Honorary Council Member, and Toshikazu Yoshikawa (Japan) Honorary Editor of Pathophysiology.

During the General Assembly, the Beijing ISP Declaration concerning the important role and position of pathophysiological teaching/learning in biomedical curricula was unanimously approved by the delegates (see. www.ispathophysiology.org/Declaration.html).

The ISP General Assembly confirmed that the 6th Congress of Pathophysiology (ISP-2010) will be held in Montreal, Canada with Pavel Hamet as Congress President and Sergei Orlov as Secretary General (www.ISPmontreal2010.com). Based on four ambitious bid presentations from Morocco with the African Association of Physiological Sciences (AAPS), Serbia, Ukraine, and Turkey, the venue of The ISP-2014 congress was decided by the new ISP Council in a secret ballot. Rabat, Morocco with Wail Benjelloun, Secretary General of AAPS, won the bid. The General Assembly during the 6th ISP Congress in Montreal will receive the Moroccan report on preparations and vote on the venue of The ISP-2014 Congress according to ISP traditions.



It has been always a significant part in the policy of the ISP Council to keep contact and to cooperate with national and international societies being interested in the field of physiological sciences. As a result, successful national and international scientific conferences were organized under the patronage of The ISP.

-                      The Third Russian Congress of Pathophysiology on “Disregulatory Pathology of Organs and Systems” (Moscow, November 9-12, 2004, Georgy N. Kryshanovsky, Serguei V. Grachev, Juriy V. Archipenko);

-                      Fourth AAPS International Congress on “Physiological Challenges in Africa” (Tetouan-Tanger, November 21-26, 2004, Wail Benjelloun);

-                      Sixth International Congress of the Worldwide Hungarian Medical Academy (Budapest, August 25-27, 2005,  László Rosivall);

-                      First Congress of Physiological Sciences of Serbia and Montenegro on “Molecular, Cellular and Integrative Basis of Health, Disease and Therapy” (Belgrade, November 9-12, 2005, Dragan Djuric, Vladimir Jakovljevic).

An important cooperation exists also with the IUPS Council.



(www.elsevier.com or www.elsevier.com/locate/pathophys)

The founder of the journal was Toshikazu Yoshikawa, Japan. He became also the first Editor-in-Chief of Pathophysiology. He was successful in negotiations with the Elsevier International Publishing House, who undertook to publish the journal. The a priori principle was that the journal subscription would be part of The ISP membership fee. Professor Yoshikawa collected the necessary number (300) of subscription fees. Unfortunately, the annual dues of ISP were decided at so low level that they could not cover the subscriptions of the journal. In order to promote the future of the journal, two regional editors were nominated: D Neil Granger to deal with matters relating to the Americas and Osmo H?nninen, to Europe.

The Publishing House Elsevier became unhappy with some delays in the publication time tables of the issues and H?nninen, as suggested by The ISP leadership, was invited to serve as Editor-in-Chief. Granger continued as Regional Editor for The Americas. Hans-Christoph Scholle and Osamu Matsuo have been serving as Regional Editors for Europe and Asia-Pacific, respectively.

At present, Elsevier is engaged in negotiations with ISP President Han and Editor-in-Chief H?nninen about how to continue, as The ISP fee system cannot cover the required financial load.



For the next 4 years, the permanent website for the Society is established in collaboration with the Goodman Cancer Research Centre at McGill University. We are looking forward to fostering the exchange of information between scientists all over the world interested in the cause of pathophysiology.



The important contribution by Osmo H?nninen and Stephen Greenwald to collecting and shaping this material is highly appreciated.


Budapest, June 22, 2007.

Emil Monos,

Past President of ISP



©2006 - 2010 International Society for Pathophysiology. All Rights Reserved.